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Index > Protein center > Cyp11b2(Gene name) > Rat
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  • Cyp11b2 (Gene name),
  • Cytochrome P450 11B2, mitochondrial (Protein name ),  C11B2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cyp11b2(Cyp11b-2);
    Protein name:
    Cytochrome P450 11B2, mitochondrial;
    Alternative:
    CYPXIB2;Aldosterone synthase;1.14.15.4;Steroid 11-beta-hydroxylase);Cytochrome P450-Aldo-1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Converts 11-deoxycorticosterone into corticosterone, 18-hydroxycorticosterone, and aldosterone. Also can catalyze the conversion of 11-deoxycortisol to cortisol, 18-hydroxycortisol and cortisone.
    Subcellular Location:
    Mitochondrion membrane
    Protein Attributes:
    Sequence length:
    510
    Sequence:
    50:
    MGACDNDFIE | LHSRVTADVW | LARPWQCLHR | TRALGTTATL | APKTLKPFEA | 
    100:
    IPQYSRNKWL | KMIQILREQG | QENLHLEMHQ | AFQELGPIFR | HSAGGAQIVS | 
    150:
    VMLPEDAEKL | HQVESILPRR | MHLEPWVAHR | ELRGLRRGVF | LLNGAEWRFN | 
    200:
    RLKLNPNVLS | PKAVQNFVPM | VDEVARDFLE | ALKKKVRQNA | RGSLTMDVQQ | 
    250:
    SLFNYTIEAS | NFALFGERLG | LLGHDLNPGS | LKFIHALHSM | FKSTTQLLFL | 
    300:
    PRSLTRWTST | QVWKEHFDAW | DVISEYANRC | IWKVHQELRL | GSSQTYSGIV | 
    350:
    AALITQGALP | LDAIKANSME | LTAGSVDTTA | IPLVMTLFEL | ARNPDVQQAL | 
    400:
    RQETLAAEAS | IAANPQKAMS | DLPLLRAALK | ETLRLYPVGG | FLERILNSDL | 
    450:
    VLQNYHVPAG | TLVLLYLYSM | GRNPAVFPRP | ERYMPQRWLE | RKRSFQHLAF | 
    500:
    GFGVRQCLGR | RLAEVEMLLL | LHHMLKTFQV | ETLRQEDVQM | AYRFVLMPSS | 
    510:
    SPVLTFRPIS | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    E9018h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    E9018m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    E9018r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    U9018m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    U9018h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    U9018r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    P9018Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    P9018Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Cytochrome P450 11B2, mitochondrial
    Cat.:
    P9018Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Cytochrome P450 11B2, mitochondrial
    Monoclonal Antibody for Rat Cytochrome P450 11B2, mitochondrial
    Monoclonal Antibody for Rat Cytochrome P450 11B2, mitochondrial
    Protein for Rat Cytochrome P450 11B2, mitochondrial
    Protein for Rat Cytochrome P450 11B2, mitochondrial
    Protein for Rat Cytochrome P450 11B2, mitochondrial

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and expression of cDNAS encoding rat aldosterone synthase: variants of cytochrome P-450(11 beta)."
      Matsukawa N. , Nonaka Y. , Ying Z. , Higaki J. , Ogihara T. , Okamoto M.
      Biochem. Biophys. Res. Commun.169:245-252(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Adrenal gland.
    2. 2.
      "Molecular biology of rat steroid 11 beta-hydroxylase [P450(11 beta)] and aldosterone synthase [P450(11 beta, aldo)]."
      Okamoto M. , Nonaka Y.
      J. Steroid Biochem. Mol. Biol.41:415-419(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning and expression of a rat cytochrome P-450 11 beta-hydroxylase/aldosterone synthase (CYP11B2) cDNA variant."
      Zhou M. , Gomez-Sanchez C.E.
      Biochem. Biophys. Res. Commun.194:112-117(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Adrenal gland.
    4. 4.
      "Three forms of rat CYP11B genes: 11 beta-hydroxylase gene, aldosterone synthase gene, and a novel gene."
      Nomura M. , Morohashi K. , Kirita S. , Nonaka Y. , Okamoto M. , Nawata H. , Omura T.
      J. Biochem.113:144-152(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION;VARIANT GLY-84
    5. 5.
      "Isolation of aldosterone synthase cytochrome P-450 from zona glomerulosa mitochondria of rat adrenal cortex."
      Ogishima T. , Mitani F. , Ishimura Y.
      J. Biol. Chem.264:10935-10938(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-54
      tissue: Adrenal cortex.
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